<p>Dear Editors;</p>
<p>I present to you with all due respect our manuscript, which is named as “Intrauterine Insemination Success Rates in Different TSH Levels” to your discretion as a publication, to be regarded as an original research<em>. </em>The manuscript has not yet been previously published or submitted to another journal as a publication.</p>
<p>There are quite a number of people who are planning for pregnancy and taking thyroid medications at the same time. Experts don’t always necessarily agree on when to start proper thyroid therapies on pregnant women. There is a possibility that some of such women may be taking the aforementioned therapies unnecessarily.</p>
<p>In our study; it was our utmost objective to investigate the relationship between TSH levels and intrauterine insemination successes in couples with unexplained infertility who were undergoing intrauterine insemination treatments. We couldn’t find any statistically significant differences in terms of intrauterine insemination successes between the control group, which was defined with TSH levels below 2.5 mIU/L and the study group, which was defined with TSH levels between 2.5 mIU/L and 4.5 mIU/L. We are aware that a lot of infertile women who possess a TSH value between 2.5 and 4.5 mIU/L are currently receiving medication, and that this fact is causing an increase in unnecessary drug use for patients, along with an increase in health expenditures.</p>
<p>We have investigated the cases between June 2017 and October 2019, who have applied to our infertility clinic. After the exclusion of a number of patients, which were excluded from the research in tandem with the exclusion criteria, a total of 225 cycles were performed in a total of 151 couples with unexplained infertility.</p>
<p>UEAH Ethics Committee approval number: B.10.1TKH.4.34.H.GP.0.01/206. &nbsp;After the performance of the cycles, we have retrospectively screened the patient files which were residing in our archives.</p>
<p>Should you have any questions about the manuscript, I shall be serving as the corresponding author. Thank you for your consideration.</p>
<p>Sincerely,</p>
<p>Ethics Committee Approval No: &nbsp;B.10.1TKH.4.34.H.GP.0.01/206</p>
<p>Gizem Berfin Uluutku</p>
<p>berfinuluutku@yahoo.com</p>
<p>&nbsp;</p>