<p>Dear Editor:</p>
<p>&nbsp;</p>
<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; We hereby submit our manuscript entitled “<em>COL4A1 and COL4A2 mutations analyses with perinatal arterial ischemic stroke</em>” to be considered for publication in Tropical Health and Medical Research. This study, containing original material and it has not been previously published and has been read and approved by all authors.</p>
<p>The aim of the present study was to establish the relation of COL4A1 and COL4A2 mutations and perinatal arterial ischemic stroke. To the best of our knowledge this is the first study about this topic. Additionally we were present maternal/perinatal risk factors of perinatal arterial ischemic stroke. &nbsp;&nbsp;</p>
<p>Thank you in advance for your efforts and the efforts of your reviewers.</p>
<p>Yours faithfully.</p>
<p>Corresponding author</p>
<p>Ozan Kocak, M.D.</p>
<p>Department of Pediatric Neurology, Osmangazi University Medicine Faculty</p>
<p>Meşelik Yerleşkesi, 26040, Eskişehir / TURKEY</p>
<p>Phone: +90 5057916232</p>
<p>E-mail: ozankocak79@gmail.com</p>
<p>ozank@ogu.edu.tr</p>