Effect of Black Garlic Extract in Feminine Liquid Soap as Antibacterial (Escherichia coli)

Effect of Black Garlic Extract in Feminine Liquid Soap as Antibacterial (Escherichia coli)

Authors

  • Putu Arik Herliawati Department of Midwifery, STIKES Advaita Medika Tabanan, Bali Indonesia
  • Ni Putu Wintariani Clinical Pharmacy Study Program, Faculty of Health Sciences, Universitas Bali Internasional, Indonesia
  • Brigita Olivia Department of Midwifery, STIKES Advaita Medika Tabanan, Bali Indonesia
  • Rezha Alivia Hildayanti Department of Midwifery, STIKES Kendedes Malang, Indonesia
  • Nanda Agnesia Jati Pratiwi Department of Midwifery, STIKES Kendedes Malang, Indonesia

DOI:

https://doi.org/10.35916/thmr.v5i1.100

Keywords:

Black garlic, Escherichia coli, feminim hygine, liquid soap

Abstract

One of the causes of infection is pathological vaginal discharge caused by Escherichia coli. Handling of this infectious disease is still limited to giving antibiotics. So, an alternative therapy is needed using herbs. Black garlic is a fermented product that has stronger antibacterial properties. Based on this, it is necessary to test the potential of liquid soap with black garlic extract as antibacterial as scientific evidence. Research Objectives: To analyze the effect of black garlic extract on women's liquid soap on the growth of Escherichia coli. This research is quantitative research with an experimental research design. In this study, the intervention given was giving black garlic extract in feminism hygiene liquid soap preparations with various doses for bacteria Escherichia coli with disc diffusion technique. Black garlic extract was tested for phytochemicals to determine the content of active compounds. The results showed that black garlic extract in feminine hygiene liquid soap inhibited the growth of Escherichia coli bacteria; at a concentration of 40%, black garlic had the highest antibacterial activity with an average inhibition zone of 12.7mm. Therefore, it is proven that black garlic extract is effective as an antibacterial Escherichia coli in the formulation of feminine hygiene liquid soap.

References

Kim K-H, Park JK, Choi Y-W, Kim Y-H, Lee EN, Lee J-R. Hexane extract of aged black garlic reduces cell proliferation and attenuates the expression of ICAM-1 and VCAM?1 in TNF-?-activated human endometrial stromal cells. Int J Mol Med. 2013;32(1):67–78.

K?dzia A. Antimicrobial activity of garlic (Allium sativum L.). Post?py Fitoter. 2010; (1):46–52.

Venugopal S, Gopalan K, Devi A, Kavitha A. Epidemiology and clinico-investigative study of organisms causing vaginal discharge. Indian J Sex Transm Dis AIDS. 2017;38(1):69.

Donders GGG, Bellen G, Rezeberga D. Aerobic vaginitis in pregnancy. BJOG An Int J Obstet Gynaecol. 2011;118(10):1163–70.

Han C, Li H, Han L, Wang C, Yan Y, Qi W. Aerobic vaginitis in late pregnancy and outcomes of pregnancy. Eur J Clin Microbiol Infect Dis. 2019;38(2):233–9.

Tao Z, Zhang L, Zhang Q, Lv T, Chen R, Wang L. The pathogenesis of Streptococcus anginosus in aerobic vaginitis. Infect Drug Resist. 2019;(7) 45–54.

Sonthalia S, Aggarwal P, Das S, Sharma P, Sharma R, Singh S. Aerobic vaginitis–An underdiagnosed cause of vaginal discharge–Narrative review. Int J STD AIDS. 2020;31(11):(10) 18–27.

Homayouni A, Bastani P, Ziyadi S, Mohammad-Alizadeh-Charandabi S, Ghalibaf M, Mortazavian AM. Effects of probiotics on the recurrence of bacterial vaginosis: a review. J Low Genit Tract Dis. 2014;18(1):79–86.

Prasad D, Parween S, Kumari K, Singh N. Prevalence, etiology, and associated symptoms of vaginal discharge during pregnancy in women seen in a tertiary care Hospital in Bihar. Cureus. 2021;13(1). 1-11

Halimah LS, Hasan K. Differences of bio (chemical) characterization of garlic and black garlic on antibacterial and antioxidant activities. In: Journal of Physics: Conference Series. IOP Publishing; 2021. (17) 64-75

Wang D, Feng Y, Liu J, Yan J, Wang M, Sasaki J. Black garlic (Allium sativum) extracts enhance the immune system. Med Aromat Plant Sci Biotechnol. 2010;4(1):37–40.

Tran G-B, Pham T-V, Trinh N-N. Black garlic and its therapeutic benefits. Med Plants-Use Prev Treat Dis. 2019; (3) 37-63

Marhaeni GA. Keputihan pada wanita. J Skala Husada J Heal. 2016;13(1) 66-78.

Yuan H, Sun L, Chen M, Wang J. The comparison of the contents of sugar, Amadori, and Heyns compounds in fresh and black garlic. J Food Sci. 2016;81(7):(6) 62–68.

Liu R, Yang G, Guo J, Wu T, Sui W, Zhang M. Effects of incorporation of black garlic on rheological, textural and sensory properties of rye (Secale Cereale l.) flour noodles. CYTA-Journal Food. 2018;16(1):1102–8.

Saifudin A. Natural Compounds Secondary Metabolites Theory. Concept, and Purification Tech, Deep Yogyakarta. 2014; (3) 45-52

Kusuma EW, Anggraini DI. Uji Antipiretik Ekstrak Etanol Bawang Hitam (Black Garlic) Pada Tikus Putih Jantan. Humantech J Ilm Multidisiplin Indones. 2022;1(7):968–79.

Zeng L, Zhang L, Shi J, Gu L, Grogan W, Gargano MM. The primary microbial pathogens associated with premature rupture of the membranes in China: a systematic review. Taiwan J Obstet Gynecol. 2014;53(4):443–51.

Wardhani GAPK, Azizah M, Hastuti LT. Value of Total Flavonoids in Black Garlic (Allium sativum L.) Based on The Solvent Fraction and Antioxidant Activity. J Agroindustri Halal. 2020;6(1):20–7.

Haris, R. S. W., Mujnisa, A. and Jamilah. Uji Daya Hambat Antibakteri Black Garlic Sebagai Alternatif Feed Additive Pada Pakan Unggas, Buletin Nutrisi dan Makanan Ternak. 2021; 15(1). doi: 10.20956/bnmt.v15i1.14463.

Widhowati D, Mudji EH, Prakoso YA, Aulia Q. Sensitivitas black garlic terhadap pertumbuhan Salmonella Sp. VITEK Bid Kedokt Hewan. 2022;12(2):16–22.

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Published

28-08-2023

How to Cite

Herliawati, P. A., Wintariani, N. P., Olivia, B., Hildayanti, R. A., & Pratiwi, N. A. J. (2023). Effect of Black Garlic Extract in Feminine Liquid Soap as Antibacterial (Escherichia coli): Effect of Black Garlic Extract in Feminine Liquid Soap as Antibacterial (Escherichia coli). Tropical Health and Medical Research, 5(2). https://doi.org/10.35916/thmr.v5i1.100